Pearl Choise
| Gender | Female |
| Age | Unknown. Likely in her 20s |
| Hair Color | Black |
| Occupation | Home Economics Teacher |
| Grade | 4th Grade |
| Aliases | Mysterion, El Pollo Loco |
| Religion | Unknown; likely Roman Catholic |
| Voiced by | Toddy Walters |
| First Appearance | Tweek vs. Craig |
Pearl is South Park Elementary's home economics teacher. She speaks with a soft, gentle voice and does her job with plenty of knowledge, yet judging by her lessons she follows stereotypical beliefs. She is good with chat up lines, as she is shown to come up with them and then have her students recite them in their lessons. She dates Mr. Adler, and she wanted to sleep with him in the episode "Tweek vs. Craig". He refused, because he had recently lost his wife and was mourning her death instead of moving on.